Begoña López Selected Research

Protein-Lysine 6-Oxidase (Lysyl Oxidase)

1/2017	MicroRNA-19b is a potential biomarker of increased myocardial collagen cross-linking in patients with aortic stenosis and heart failure.
12/2016	Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment.
7/2013	Osteopontin-mediated myocardial fibrosis in heart failure: a role for lysyl oxidase?
9/2012	Collagen cross-linking but not collagen amount associates with elevated filling pressures in hypertensive patients with stage C heart failure: potential role of lysyl oxidase.
7/2010	Role of lysyl oxidase in myocardial fibrosis: from basic science to clinical aspects.
2/2009	Impact of treatment on myocardial lysyl oxidase expression and collagen cross-linking in patients with heart failure.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Begoña López Research Topics

Disease

46	Fibrosis (Cirrhosis) 10/2023 - 05/2002
43	Heart Failure 10/2023 - 06/2004
17	Heart Diseases (Heart Disease) 01/2021 - 12/2002
14	Hypertension (High Blood Pressure) 01/2021 - 11/2003
8	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 08/2012 - 08/2004
7	Hypertrophy 08/2012 - 03/2005
6	Atrial Fibrillation 04/2024 - 10/2014
6	Left Ventricular Dysfunction 06/2022 - 04/2006
6	Aortic Valve Stenosis (Aortic Stenosis) 04/2020 - 04/2014
5	Chronic Renal Insufficiency 10/2020 - 12/2008
3	Inflammation (Inflammations) 01/2022 - 10/2011
3	Systolic Heart Failure 10/2014 - 07/2006
3	Essential Hypertension 11/2007 - 01/2002
2	Diastolic Heart Failure 10/2017 - 07/2006
2	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 02/2015 - 08/2010
2	Pathologic Processes 08/2012 - 04/2005
1	Thrombosis (Thrombus) 04/2024
1	Ischemic Stroke 04/2024
1	Cardiotoxicity 06/2022
1	Breast Neoplasms (Breast Cancer) 06/2022
1	Neoplasms (Cancer) 06/2022
1	Malnutrition (Nutritional Deficiencies) 01/2022
1	Infections 01/2022
1	Stroke (Strokes) 01/2022
1	Ventricular Remodeling 01/2019
1	Pathologic Constriction (Stenosis) 12/2016
1	Type 2 Diabetes Mellitus (MODY) 04/2015
1	Myocardial Infarction 01/2014
1	Kidney Diseases (Kidney Disease) 11/2013

Drug/Important Bio-Agent (IBA)

35	Biomarkers (Surrogate Marker)IBA 04/2024 - 08/2004
35	CollagenIBA 10/2023 - 05/2002
16	Collagen Type I (Type I Collagen)IBA 01/2023 - 11/2003
12	Procollagen Type IIBA 01/2023 - 08/2005
9	procollagen type I carboxy terminal peptide (PICP)IBA 01/2023 - 09/2007
7	Angiotensin IIIBA 01/2020 - 01/2002
6	Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA 01/2017 - 02/2009
6	CytokinesIBA 08/2012 - 03/2005
5	Proteins (Proteins, Gene)FDA Link 04/2024 - 10/2007
5	Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA 01/2023 - 03/2004
5	Peptides (Polypeptides)IBA 01/2023 - 08/2005
5	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2019 - 03/2014
5	Torsemide (Demadex)FDA LinkGeneric 01/2018 - 06/2004
5	Antihypertensive Agents (Antihypertensives)IBA 12/2005 - 12/2002
4	EnzymesIBA 01/2017 - 03/2004
4	MicroRNAs (MicroRNA)IBA 01/2017 - 04/2014
3	Spironolactone (Aldactone)FDA LinkGeneric 01/2022 - 01/2018
3	Collagen Type III (Type III Collagen)IBA 01/2019 - 03/2014
3	SaltsIBA 01/2019 - 04/2006
3	Troponin T (Troponin T1)IBA 01/2019 - 12/2016
3	Furosemide (Lasix)FDA LinkGeneric 01/2018 - 06/2004
3	Losartan (Cozaar)FDA LinkGeneric 01/2017 - 05/2002
3	Tissue Inhibitor of Metalloproteinase-1IBA 01/2016 - 06/2010
2	Galectin 3 (LGALS3)IBA 01/2021 - 04/2015
2	Matrix Metalloproteinases (MMPs)IBA 02/2020 - 03/2004
2	procollagen Type III-N-terminal peptide (PIIP)IBA 01/2019 - 04/2015
2	GadoliniumIBA 01/2018 - 08/2010
2	CreatinineIBA 09/2017 - 03/2009
2	Connective Tissue Growth FactorIBA 01/2017 - 11/2013
2	pro-brain natriuretic peptide (1-76)IBA 12/2016 - 02/2009
2	OsteopontinIBA 01/2016 - 07/2013
2	NADPH Oxidases (NAD(P)H oxidase)IBA 11/2013 - 01/2012
2	Superoxides (Superoxide)IBA 11/2013 - 01/2012
2	Messenger RNA (mRNA)IBA 11/2013 - 10/2007
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 05/2011 - 03/2006
2	Natriuretic PeptidesIBA 03/2009 - 02/2009
2	Sodium Potassium Chloride Symporter Inhibitors (Loop Diuretics)IBA 12/2008 - 06/2004
2	Atenolol (Tenormin)FDA LinkGeneric 09/2007 - 08/2004
2	Fibrillar CollagensIBA 03/2004 - 12/2002
1	AnthracyclinesIBA 06/2022
1	ProcollagenIBA 06/2022
1	Prealbumin (Transthyretin)IBA 01/2022
1	citrus pectinIBA 01/2021
1	Insulin-Like Growth Factor Binding Protein 2IBA 10/2020
1	Amphibian VenomsIBA 01/2020
1	lycorineIBA 01/2020
1	bufalinIBA 01/2020
1	AlkaloidsIBA 01/2020
1	SteroidsIBA 01/2020
1	Histones (Histone)IBA 01/2020
1	Long Noncoding RNAIBA 01/2019
1	Fibroblast Growth Factor-23IBA 01/2019
1	Mineralocorticoid Receptor AntagonistsIBA 01/2019
1	PlasticsIBA 01/2018
1	ProteomeIBA 09/2017
1	NG-Nitroarginine Methyl Ester (L-NAME)IBA 01/2017
1	losartan carboxylic acidIBA 01/2017
1	2- butyl- 4- chloro- 1- ((2'- (1H- tetrazol- 5- yl)(1,1'- biphenyl)- 4- yl)methyl)- 1H- imidazole- 5- carboxaldehydeIBA 01/2017
1	CalciumIBA 10/2016
1	Cystatin CIBA 01/2016
1	Glucagon-Like Peptide 1 (GLP 1)IBA 04/2015
1	Diltiazem (Cardizem)FDA LinkGeneric 02/2015
1	Transforming Growth Factors (Transforming Growth Factor)IBA 04/2014
1	ConnectinIBA 11/2013
1	Interleukin-6 (Interleukin 6)IBA 08/2012
1	OSM-LIF ReceptorsIBA 08/2012

Therapy/Procedure

11	Therapeutics 10/2023 - 08/2004
1	Secondary Prevention 04/2024
1	Drug Therapy (Chemotherapy) 06/2022
1	Thrombectomy 01/2022
1	Transplantation 01/2014